熊本キャンパス 八代キャンパス
情報通信
エレクトロニクス
工学科
制御情報システム
工学科
人間情報システム
工学科
共通教育科 機械知能システム
工学科
建築社会デザイン
工学科
生物化学システム
工学科
共通教育科
研究者情報(教員一覧)

学術論文

  1. M. Hyakutake, S. Tomizawa, I. Sugahara, E. Murata, K. Mizuno, H. Abe, T. Tsuge,
    "Carboxy-Terminal Modification of Polyhydroxyalkanoate (PHA) via Alcoholysis Reaction Catalyzed by Class IV PHA Synthase",
    Polym. Degrad. Stab., 117, 90?96 (2015).,
  2. M. Hyakutake, S. Tomizawa, K. Mizuno, T. Hisano, H. Abe, T. Tsuge,
    "A common active site of polyhydroxyalkanoate synthase from Bacillus cereus YB-4 is involved in polymerization and alcoholysis reactions",
    Appl. Microbiol. Biotechnol., 99(11), 4701-4711 (2015).,
  3. S. Tomizawa, JA. Chuah, K. Matsumoto, Y. Doi, K. Numata,
    "Understanding the limitations in the biosynthesis of Polyhydroxyalkanoate (PHA) from lignin derivatives",
    ACS Sustainable Chemistry & Engineering, 2(5), 1106-1113 (2014).,
  4. M. Hyakutake, S. Tomizawa, K. Mizuno, H. Abe, T. Tsuge,
    "Alcoholytic cleavage of polyhydroxyalkanoate chains by class IV synthases induced by endogenous and exogenous ethanol",
    Appl. Environ. Microbiol., 80(4), 1421-1429 (2013).,
  5. S. Tomizawa, S. Sato, J. C. W. Lan, Y. Nakamura, H. Abe, T. Tsuge,
    "In vitro evidence of chain transfer to tetraethylene glycols in enzymatic polymerization of polyhydroxyalkanoate ",
    Appl. Microbiol. Biotechnol., 97(11), 4821-4829 (2013).,
  6. JA Chuah, S. Tomizawa, M. Yamada, T. Tsuge, Y. Doi, K. Sudesh, K. Numata,
    "Characterization of site-specific mutations in a short-chain-length/medium-chain-length polyhydroxyalkanoate synthase: in vivo and in vitro studies of enzymatic activity and substrate specificity ",
    Appl. Environ. Microbiol., 79(12), 3813-3821 (2013).,
  7. K. Numata, K. Morisaki, S. Tomizawa, M. Ohtani, T. Demura, M. Miyazaki, Y. Nogi, S. Deguchi, Y. Doi,
    "Synthesis of poly- and oligo(hydroxyalkanoate)s by deep-sea bacteria, Colwellia spp., Moritella spp., and Shewanella spp",
    Polymer Journal, 45(10), 1094-1100 (2013).,
  8. S. Tomizawa, M. Yoshioka, K. Ushimaru, T. Tsuge,
    "Preparative synthesis of poly[(R)-3-hydroxybutyrate] monomer for enzymatic cell-free polymerization",
    Polymer Journal, 44(9), 982-985 (2012).,
  9. M. Hyakutake, Y. Saito, S. Tomizawa, K. Mizuno, T. Tsuge,
    "Polyhydroxyalkanoate (PHA) synthesis by class IV PHA synthases employing Ralstonia eutropha PHB-4 as a host strain",
    Biosci. Biotechnol. Biochem., 75(8), 1615-1617 (2011).,
  10. S. Tomizawa, M. Hyakutake, Y. Saito, J. Agus, K. Mizuno, H. Abe, T. Tsuge,
    "Molecular weight change of polyhydroxyalkanoate (PHA) caused by the PhaC subunit of PHA synthase from Bacillus cereus YB-4 in recombinant Escherichia coli",
    Biomacromolecules, 12(7), 2660-2666 (2011).,
  11. J. Agus, P. Kahar, M. Hyakutake, , S. Tomizawa, H. Abe, T. Tsuge, Y. Satoh, K. Tajima,
    "Unusual change in molecular weight of polyhydroxyalkanoate (PHA) during cultivation of PHA-accumulating Escherichia coli",
    Polym. Degrad. Stab. 95(12), 2250-2254 (2010).,
  12. S. Tomizawa, Y. Saito, M. Hyakutake, Y. Nakamura, H. Abe, T. Tsuge,
    "Chain transfer reaction catalyzed by various polynydroxyalkanoate synthases with poly (ethylene glycol) as an exogenous chain transfer agent",
    Appl. Microbiol. Biotechnol. 87(4), 1427-1435 (2010).,
  13. T. Tsuge, Y. Hamada, Y. Watanabe, S. Tomizawa, T. Yamamoto, H. Abe,
    "Characterization of biosynthesized P(3HB-co-3HA)s swellable in organic solvents",
    Polym. Degrad. Stab., 95(8),1345-1348 (2010).,

国際学会等発表

  1. 富澤哲, 渡辺友香, JA Chuah, 土肥義治, 沼田圭司,
    "Biosynthesis of Lipase-degradable Polyhydroxyalkanoate containing 5-hydroxyvalerate units",
    International Symposium on Bioppolymers 2012, Cairns, 2012/10/7-10,
  2. 富澤哲, 百武真奈美, 斉藤雄太, J. Agus, 水野康平, 阿部英喜, 柘植丈治,
    "Molecular Weight Change of Polyhydroxyalcanoate (PHA) Caused by PhaC Subunit of Class IV PHA Synthase in Recombinant Escherichia coli",
    The 3rd International Conference on Bio-Based Polymers, Beijing, 2010/10/18-21,

国内学会等発表

  1. 富澤哲, 沼田圭司,
    "ポリヒドロキシアルカン酸重合酵素の芳香族モノマーに対する活性の検討",
    第63回高分子討論会, 長崎, 2014/9/24-26,
  2. 富澤哲, 沼田圭司,
    "ポリヒドロキシアルカン酸を合成する微生物による芳香族カルボン酸の変換",
    第62回高分子討論会, 金沢, 2013/9/11-13,
  3. 富澤哲, 渡辺友香, 沼田圭司,
    "Synthesis of polyhydroxyalkanoate (PHA) from aromatic carboxylic acid as a sole carbon source by PHA accumulation",
    第62回高分子学会年次大会, 京都, 2013/5/29-31,
  4. 富澤哲, 中村義之, 阿部英喜, 柘植丈治,
    "P(3HB)の生体外重合における連鎖移動反応の解析",
    第61回高分子学会年次大会, 神奈川, 2012/5/29-31,
  5. 富澤哲, 阿部英喜, 柘植丈治,
    "PHB重合機構解析のためのin vitro重合法の検討",
    農芸化学会2011年度大会, 京都, 2011/3/25,

解説・総説

  1. S. Tomizawa, JA. Chuah, M. Ohtani, T. Demura, K. Numata,
    "Biosynthesis of Polyhydroxyalkanoate by Marine Bacteria Vibrio sp. using sugars, plant oil and unsaturated fatty acids as a sole carbon source",
    Green Polymer 2, American Chemical Society Series Book, Chapter 15, 211-221 (2013).,

特許

  1. 特開2015-077103
     微生物によるポリヒドロキシアルカン酸の生産方法
  2. 特開2015-029484
     低分子量ポリヒドロキシアルカン酸の製造方法